CRBSI is a complex medical problem that challenges the viability
of extended use of bloodstream catheters, due to bloodstream infections often caused by the catheters, or
at least bacteria that gathers around the catheters either inside the bloodstream, or at
the entry site. The medical world has been trying to tackle CRBSI for well over a
decade. CRBSI is an acronym for catheter-related bloodstream infections. In the United States
intensive care units (ICUs) alone, there are 15 million "central venous catheter (CVC) days" each year.
During that same time frame, there are an average of 80,000 CRBSI cases in those ICUs, and 250,000 CRBSI
cases in the entire hospital. These infections represent a considerable toll on patients and
hospital resources. There are additional CRBSI cases outside the hospital environments, for example in
ambulatory dialysis patients, who visit outpatient dialysis clinics several times per week.
The United States Centers
for Disease Control (CDC) has developed guidelines to try to help minimize CRBSI occurence, that includes measures
such as good aseptic protocols, avoidance of certain kinds of susceptible catheters, placement of catheters, daily
site care protocols, and more. Prevention measures go a long way to slow the occurence of CRBSI, but are not
total solutions, as the statistics show. Innovative prevention measures are in the pipeline, and are only
hindered by the juggernaut and politics at the FDA.
The treatment of CRBSI
has been hampered by an alarming and growing resistance to antibiotics that have traditionally been used to fight
bloodstream infections. This is often referred to as MRSA (methicillin resistant staph aureus) and MRSE
(methicillin resistant staphyloccus epidermus), along with some other bacteria strains that are vancomycin
resistant. CRBSI falls in the broader category of hospital acquired infections (HAIs) and as such, not only
is it difficult medically to resolve, but it also represents significant liability risk in the clinical
setting. The toll on patients, physicians, caregivers and the clinics all make for great urgency to get
treatments approved and available to clinicians stat.
We plan to develop this
site into a comprehensive CRBSI resource site in the coming months. We thank you for visiting
CRBSI.com now, and in the future as the site evolves. Feel free to contact us if
you have anything to add.